Owing to pseudoexfoliation glaucoma’s prevalence and severity, gonioscopy should be performed to assess for pigment deposition and a Sampaolesi’s line. Sampaolesi line is a sign which may be observed during a clinical eye examination. During gonioscopy if an abundance of brown pigment is seen at or anterior. The Glaucomas. Volume II – Open Angle Glaucoma and Angle Closure Glaucoma. Authors; (view affiliations). Roberto Sampaolesi; Juan Roberto Sampaolesi.

Author: Dorr Molkis
Country: Morocco
Language: English (Spanish)
Genre: Travel
Published (Last): 9 July 2010
Pages: 465
PDF File Size: 7.34 Mb
ePub File Size: 12.54 Mb
ISBN: 400-3-65424-891-2
Downloads: 59095
Price: Free* [*Free Regsitration Required]
Uploader: Voodoolkis

Pseudoexfoliative Glaucoma – EyeWiki

This page has been accessedtimes. Midperipheral iris transillumination defects occur in pigment dispersion syndrome.

Pseudoexfoliation of the lens capsule. This is most easily seen after dilatation, and is therefore sometimes overlooked Figures Aggarwal JL, Beveridge B. The higher IOP observed in pseudoexfoliation glaucoma can lead to more rapid optic nerve damage and visual field loss. Retrieved from ” http: Cyclodestruction of the ciliary body last resort. Challa is assistant professor of ophthalmology on the glaucoma service and residency director at the Duke University Eye Center in Durham, N.

Actual pseudoexfoliative material may be noted on the TM.

Get free access to newly published articles Create a personal account or sign in to: Iris sphincter transillumination defects in exfoliation syndrome result from the dispersion of pigment into the anterior chamber. The cyclopentolate provocative test in suspected or untreated open-angle glaucoma: Patients who do develop PXF glaucoma are thought to have a worse prognosis than patients with POAG, with faster rates of progression, poorer response to medications and an increased need for surgery.


Purchase access Subscribe to JN Learning for one year. The axial length of normal eyes was found to increase with age. It is the most common cause of secondary glaucoma worldwide, and the most frequent cause of unilateral glaucoma.

Delayed intraocular pressure elevation after pupillary dilation in exfoliation syndrome ARVO abstract. Not reviewed add Contributing Editors: Residents and Fellows contest rules International Ophthalmologists contest rules.

When symptoms are present in one eye, the contralateral eye must be examined carefully and monitored, since pseudoexfoliation glaucoma will develop in the other eye of more than 40 percent of these patients. The examination and treatment of these patients is similar to that described earlier for exfoliation syndrome. Shihadeh may be reached at ; wisam97 yahoo. The Requisites in Ophthalmology.

Create a free personal account to download free article PDFs, sign up for alerts, customize your interests, and more. Histochemically, pseudoexfoliative material is glycoconjugates surrounding a protein core.

Pseudoexfoliative Glaucoma

Pilocarpine drops are poorly tolerated, however, because of accommodative spasm and induced myopia in younger patients. Many pedigrees have been published that demonstrate an autosomal dominant inheritance. There is also an increased risk of complications due to poor pupil dilatation and zonular weakness. In addition, there is an increased incidence of capsular rupture, vitreous loss and zonular dehiscence during cataract extraction in patients with pseudoexfoliation syndrome.

Iridozonular contact during accommodation as well as during normal pupillary constriction and dilation glaucoa the iris pigment epithelium and results in the deposition of pigmentary granules throughout the anterior segment. By preventing the liberation of pigment from the iris, laser iridotomy should allow the trabecular meshwork to clear itself and avoid further pigmentary deposition.


Current research on pseudoexfoliation syndrome is centered on genetic factors that predispose certain populations to its development. Get free access to newly published articles. Pseudoexfoliation syndrome does, however, significantly predispose those affected to the development of increased IOP, and it results in glaucoma in 15 percent to 30 percent of cases.

Submit manuscripts to sampao,esi aao.

This article is from June and may contain outdated material. Thank you Your feedback has been sent. As a result, adjunctive therapy with other medications or laser treatment is often necessary.

Ocular Echometry in the Diagnosis of Congenital Glaucoma.

Ocular Echometry in the Diagnosis of Congenital Glaucoma | JAMA Ophthalmology | JAMA Network

A larger capsulorhexis should be made at the time of surgery to prevent anterior capsule opacification and contraction. Mauricio E Pons, MD. Researchers have been able to identify pseudoexfoliation as the cause of more than 50 percent of the cases of open-angle glaucoma in Scandinavian countries.

Hypoxia can cause atrophy of the iris pigment epitheliumstroma, and glauccoma. Pseudoexfoliation glaucoma commonly presents unilaterally with IOP that tends to escalate faster than among patients with primary open-angle glaucoma POAG. Patients with pseudoexfoliation syndrome and no evidence of glaucoma are generally not treated, but they should be followed every six to 12 months as they have an increased risk of developing glaucoma.